±³À°¸í | [¸ÓÅ© ¿þºñ³ª] Multi-targeting Fc-Fusion Proteins To Accelerate Clinical Development Through GI-SMART Technologies | ºÐ·ù | ¼¼¹Ì³ª |
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½ÅûÀÏÁ¤ | 2023.08.09~2023.09.12 | Çà»çÀÏÁ¤ | 2023.09.12~2023.09.12 |
Àå¼Ò | ¿Â¶óÀÎ ¿þºñ³ª | ½Ã°£ | 15:00 - 16:00 |
[Merck] ÇÔ²²ÇØ¿ä. APeC ¿þºñ³ª
Multi-targeting Fc-Fusion Proteins To Accelerate Clinical Development Through GI-SMART Technologies
✅ ÁÖÁ¦: Multi-targeting Fc-Fusion Proteins To Accelerate Clinical Development Through GI-SMART Technologies
✅ ÀÏÁ¤: 2023³â 9¿ù 12ÀÏ(È) ¿ÀÈÄ 3½Ã-4½Ã (KST)
The identification of proteins and their stable production cell line construction (CLD) that ensures developability are crucial points to quickly reach clinical phase 1. To achieve this, GI Innovation, Inc. developed the CHOZN platform with flexible protein quality adjustment with stable productivity.
However, the CLD for multi-specific Fc-fusion proteins is revealing more developmental challenges than single-targeting antibodies, such as reduced target protein expression and decreased yield of single protein yield because of its structural stability. In this presentation, I would like to share our SMART-Selex and SMART-cLego technologies for overcoming these complex hurdles.
In this webinar, you will learn:
l SMART-CLD: Enhanced Cell Line Development Method
l SMART-Selex: Optimal multi-specific protein modeling through AI-assisted structural library
l SMART-cLego: Efficient and fast generation of expression vectors for structural variants of multi-specific protein
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